Reference source : Workplace Safety Portal-ISHL
On 26 June 2026, Japan’s Ministry of Health, Labour and Welfare (MHLW) released a list of 169 new chemicals under the Industrial Safety and Health Act (ISHA). The same day, an official ISHA Notice was published, and the MHLW's Workplace Safety Portal was updated with information on the new chemicals. The portal includes official gazette serial numbers, chemical names, and structural formulas. The list of new chemical substances can be found here.
Previous Update in March 2026
Previously, on 27 March 2026, the MHLW added 171 new chemical substances to the ISHL inventory. More information can be found here.
ISHL Inventory
The ISHL Inventory consists of two parts:
1. Existing chemical substances under:
2. New substances notified under the ISHL and published on the Official Gazette
The ministry publishes updates to this list several times a year, and the total number of substances made public under ISHA now stands at 73,376.
Obligations for Stakeholders
Once listed, manufacturers and importers are no longer required to notify MHLW prior to manufacturing or importing these substances. The substances are included in MHLW’s publicly accessible database of chemical substances under ISHA, which serves as a key reference for identifying substances subject to workplace chemical management requirements.
Companies handling these substances must continue to comply with applicable obligations, including hazard communication, such as the provision of Safety Data Sheets (SDS), appropriate labelling, and the implementation of risk management measures to protect workers.
Chemicals that are not yet listed in the ISHL inventory must be notified under the new chemical notification requirements based on the applicable tonnage.