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EPA Updates Safer Chemical Ingredients List with Addition of 18 New Chemicals

2025-08-14 Reference source : US EPA

US TSCA Environmental Protection Agency EPA Safer Chemical Ingredients List SCIL SCIL Update Safer Alternatives EPA Update Safer Choice Program New Chemical Additions


On 21 July 2025, the U.S. Environmental Protection Agency (EPA) announced the addition of 18 chemicals to the Safer Chemical Ingredients List (SCIL), advancing Administrator Zeldin’s commitment to transparency, innovation, and safer chemistry.

Under the Toxic Substances Control Act (TSCA), new chemicals cannot enter the U.S. market without EPA approvement. This can slow the introduction of innovative chemistries and result in older substances remaining in use longer. Expanding SCIL helps address this by identifying existing chemicals that meet Safer Choice criteria, offering manufacturers and consumers clearer access to safer alternatives.

SCIL Additions Offer Safer Alternatives

Adding existing chemicals to the Safer Chemical Ingredients List (SCIL) supports consumers, businesses, and buyers in choosing chemicals that are among the safest for their intended uses. It also helps manufacturers identify safer substitutions that meet the Safer Choice program’s criteria

Newly Added Chemicals to SCIL

Sr.no.CASList NameTSCA Chemical Name
113945-76-1Lauryl laurateDodecanoic acid, dodecyl ester
267762-27-0Cetearyl alcoholAlcohols, C16-18
313257-34-6Sodium arachidateEicosanoic, sodium salt (1:1)
471-23-8Propyl alcohol1-Propanol
529806-73-32-Ethylhexyl palmitateHexadecanoic acid, 2-ethylhexyl ester
6123-99-9Azelaic acidNonanedioic acid
79067-32-7Sodium hyaluronateHyaluronic acid, sodium salt
868648-59-9Siloxanes and Silicones, di-Me, di-Ph, polymers with Ph silsesquioxanesSiloxanes and Silicones, di-Me, di-Ph, polymers with Ph silsesquioxanes
968915-31-1Sodium polyphosphatesPolyphosphoric acids, sodium salts
10110-30-5N,N'-Ethylenebis(stearamide)Octadecanamide, N,N'-1,2-ethanediylbis-
111592-23-0Calcium stearateOctadecanoic acid, calcium salt (2:1)
1226658-19-5Sorbitan tristearateSorbitan, trioctadecanoate
13595585-15-2D-Glucurono-D-gluco-6-deoxy-L-mannan, acetate, calcium magnesium potassium sodium saltD-Glucurono-D-gluco-6-deoxy-L-mannan, acetate, calcium magnesium potassium sodium salt
148013-07-8Epoxidized soybean oil (ESBO)Soybean oil, epoxidized
1561791-00-2Ethoxylated tall oil fatty acidsFatty acids, tall-oil, ethoxylated
16141-97-9Ethyl acetoacetateButanoic acid, 3-oxo-, ethyl ester
1793334-37-3Oils, palm, stearins, hydrogenatedPalm oil, stearins, hydrogenated
1868514-74-9Hydrogenated palm oilPalm oil, hydrogenated

For additional background and information about a previous update and more information on Safer Chemical Ingredients List (SCIL), please refer to the EPA Updates Safer Chemical Ingredients List with Addition of 27 New Chemicals.



We acknowledge that the above information has been compiled from US EPA.

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