EPA Finalizes SNURs for Select TSCA Chemical Substances

On July 17, 2025, the U.S. Environmental Protection Agency (EPA) published a final rule in the Federal Register (90 FR 33283), establishing Significant New Use Rules (SNURs) under Toxic Substances Control Act (TSCA). These rules apply to several chemical substances previously reviewed through premanufacture notices (PMNs) and also subject to TSCA Orders issued by EPA.

New Use Notification Requirement 
Under the SNURs, any person intending to manufacture (including import) or process the listed chemical substances for a use designated “significant new use” must submit a Significant New Use Notice (SNUN) to EPA at least 90 days in advance. This notification initiates EPA's evaluation of the intended use and ensures that manufacturing or processing cannot begin until EPA has completed its review and taken any required actions.

Effective and Promulgation Dates 
Final rule is codified under 40 CFR Part 721 and becomes effective on September 15, 2025.

Access to Rule Documents 
The final rule and supporting documents are available in Docket EPA-HQ-OPPT-2024-0079 on Regulations.gov. The measure was previously notified to the World Trade Organization under the symbol G/TBT/N/USA/2171 and the final text is provided through Addendum 1.

EPA encourages stakeholders to review the final rule carefully to ensure full compliance with the SNUR notification requirements before undertaking any new use of the listed substances.