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On 10 September 2025, Japan’s Ministry of Health, Labour and Welfare (MHLW) amended the list of model SDS information of chemical substances. Amended list was published on the Japan’s Workplace Safety Site on the same day. This time MHLW added 135 new chemicals and revised 140 existing chemicals to the list. Also CAS numbers and chemicals name are published on the portal.

List of GHS-compliant model SDS information

As a guide for creating SDSs based on the Globally Harmonized System of Classification and Labelling of Chemicals (GHS), the GHS-compliant model SDS information was developed. Consequently, companies use this knowledge about chemical substances as a guide when creating SDSs and other documents. Currently model list has 3,622 chemicals information available for SDS.

Previous update in October 2024

On 1 October 2024, MHLW added model SDS information for 68 new chemicals while 104 existing chemicals were revised. More details can be found here.

Obligations for Stakeholders

The Industrial Safety and Health Act (ISHA) of Japan imposes SDS delivery requirements on the manufacturers, importers, suppliers, and employers. Other literature, test findings, etc., can be used in addition to the material in this list.

On 1 September 2025, Japan’s Ministry of Economy, Trade and Industry (METI) released draft to amend provisions of Export Approval for Chemical Substances under Export Trade Control Order. Consultation notice was published on the Japan’s e-GOV Public Comment Portal. The Japanese Export Trade Control Order is a key regulation under the Foreign Exchange and Foreign Trade Act.

Export Trade Control Order

Under the Japanese Export Trade Control Order (Cabinet Order No. 378 of 1949), the export of certain chemical substances is strictly regulated through an export approval system administered by the Ministry of Economy, Trade and Industry (METI). This framework aligns Japan with international obligations under the Rotterdam and Stockholm Conventions and the Chemical Substances Control Law (CSCL). Exporters must obtain prior authorization when shipping hazardous chemicals such as pesticides, persistent organic pollutants (POPs), mercury compounds, asbestos, and PFAS, including mixtures, formulations, and even finished products containing these substances. The system ensures that Japan fulfills its role in safeguarding human health, the environment, and international security by preventing the uncontrolled transfer of dangerous chemicals.

Provisions drafted under Consultation Notice

Revised provisions are summarised in below table:

Comment Period and Enforcement Dates

Stakeholders are informed to submit comment on this draft provisions by 2 October 2025. While METI has not published the enforcement dates yet.