China Updates Management Rules for Used Cosmetic Ingredients Catalogue

On June 24, 2025, China’s National Medical Products Administration (NMPA) released Announcement No. 61 of 2025 to improve the management of cosmetic ingredients and encourage innovation in the cosmetics industry. The notice introduces updates to the Catalogue of Used Cosmetic Ingredients in China (called the “Catalogue”). 

New Ingredients Added After 3-Year Monitoring 
According to the Cosmetics Supervision and Administration Regulation, cosmetic ingredients that have been registered, filed, and completed a 3-year safety monitoring period without any safety concerns can be added to the Catalogue. The Catalogue is now divided into two parts: 

• List I: Based on the 2021 version with updates. 
• List II: For newly added ingredients after safety monitoring. 

Updates to List I: Improved Clarity and Standardization

The NMPA has made the following changes to List I: 

• The “maximum historical use level” is no longer shown. 
• Ingredient names (in Chinese or INCI/English) have been standardized. 
• Notes for some ingredients have been updated based on the Cosmetic Safety Technical Standards.

New Additions to List II

Two new ingredients have been added to List II after completing the required safety monitoring: 

• N-Acetylneuraminic Acid (CAS no. 131-48-6) 
• Beta-Alanyl-Hydroxyprolyl-Diaminobutyryl Benzylamide (CAS no. 823202-99-9)

Dynamic Updates from Now On

The Catalogue will be updated regularly based on scientific research, industry needs, and regulatory experience. Updates will no longer be announced by official notices. Instead, the latest version of the Catalogue and explanations for changes will be published on the NMPA website. 

For more details, companies can visit the official notice here   or contact their local environmental authority