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NMPA Updates Cosmetic Ingredient Catalog with Three Newly Monitored Substances

2025-10-21 Reference source : NMPA

National Medical Products Administration NMPA China Inventory of Existing Cosmetic Ingredients in China IECIC Cosmetic Regulations Monitoring Procedures


On October 20, the National Medical Products Administration (NMPA) announces the second dynamic adjustment to the Catalog of Already Used Cosmetic Ingredients (hereafter referred to as the “Catalog”), in accordance with relevant provisions.

Three cosmetic ingredients:

Lauryl Propyl Amino Acid (CAS: 5538-95-4)

Polymethylsilsesquioxane/Trimethylsiloxysilicate (CAS: 1402155-47-8)

Bis-Quaternium-Modified Dimethicone (CAS: 106214-84-0)


have completed their three-year safety monitoring period. Following evaluation, they have been deemed compliant with the Cosmetics Supervision and Administration Regulations and other relevant requirements, and have been included in Category II of the Catalog. Meanwhile, Category I of the Catalog has been updated to standardize the Chinese names and INCI/English names of certain ingredients.

In addition, the Catalog’s online query page now features a “Revision Suggestions” function, allowing industry players and the public to submit feedback and recommendations. The NMPA stated that all received opinions will be carefully reviewed and considered to continuously improve and update the Catalog.



We acknowledge that the above information has been compiled from NMPA.

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