News Details
EU Publishes 23rd ATP to CLP Regulation – New Classifications Apply from February 2027
The European Commission has adopted the 23rd Adaptation to Technical Progress (ATP) to the Classification, Labelling and Packaging (CLP9 Regulation (EC) No 1272/2008 through Delegated Regulation (EU) 2025/1222. This update concerns the harmonised classification and labelling of several chemical substances.
This amendment, based on opinions from the European Chemicals Agency’s Risk Assessment Committee (RAC), was adopted on 2 April 2025 and published in the Official Journal of the EU on 20 June 2025. It will enter into force on 10 July 2025, 20 days after publication, and become mandatory on 1 February 2027. Suppliers may apply the updated classifications voluntarily from the date of entry into force.
New Substance Entries
The following substances have been added to Table 3 of Annex VI with harmonised classifications.
|
Substance |
CAS Number |
Hazard Classification |
|
2-ethylhexanoic acid, monoester with propane-1,2-diol |
85114-00-7 |
Repr. 1B (H360D) |
|
N-1-naphthylaniline; N-phenylnaphthalen-1-amine |
90-30-2 |
Acute Tox. 4 (H302), STOT RE 2 (H373), Skin Sens. 1 (H317) |
|
tetrairon tris(pyrophosphate); ferric pyrophosphate |
10058-44-3 |
Eye Irrit. 2 (H319) |
|
α,α’-propylenedinitrilodi-o-cresol |
94-91-7 |
Repr. 1B (H360FD) |
|
ozone |
10028-15-6 |
Multiple incl. Ox. Gas 1, Carc. 2, Muta. 2, Acute Tox. 1, STOT SE 1 |
|
dinitrogen oxide |
10024-97-2 |
Repr. 1B (H360Df), STOT SE 3, STOT RE 1, Ozone 1 |
|
barium chromate |
10294-40-3 |
Carc. 1B (H350) |
|
Chrysanthemum extract (CO2) |
89997-63-7 |
Multiple incl. Acute Tox. 4, STOT SE 1, Aquatic Acute 1 |
|
Chrysanthemum extract (hydrocarbon) |
89997-63-7 |
Multiple incl. Acute Tox. 4, STOT SE 1, Aquatic Acute 1 |
|
C.I. Pigment Red 53:1 |
5160-02-1 |
Carc. 2 (H351) |
|
2-bromo-2-(bromomethyl)pentanedinitrile |
35691-65-7 |
Acute Tox. 2, Eye Dam. 1, Aquatic Chronic 2 |
|
9-octadecenoic acid (Z)-, sulfonated, potassium salts |
68609-93-8 |
Repr. 1B (H360D) |
|
bixlozone |
81777-95-9 |
Aquatic Acute 1, Aquatic Chronic 1 |
|
2,3-epoxypropyl isopropyl ether |
4016-14-2 |
Repr. 1B (H360F) |
|
tetrahydrofurfuryl methacrylate |
2455-24-5 |
Repr. 1B (H360Df), Skin Sens. 1A (H317) |
|
trimethyl phosphate |
512-56-1 |
Carc. 1B, Muta. 1B, Repr. 1B, Acute Tox. 4, STOT RE 2 |
|
fluoroethylene |
75-02-5 |
Carc. 1A (H350), Muta. 2 (H341) |
|
2-bromo-3,3,3-trifluoroprop-1-ene |
1514-82-5 |
Repr. 1B, STOT SE 3 |
|
2-methyl-2H-isothiazol-3-one hydrochloride |
26172-54-3 |
Multiple incl. Acute Tox. 2, Skin Corr. 1, Skin Sens. 1A |
|
2,3-epoxypropyl o-tolyl ether |
2210-79-9 |
Skin Irrit. 2, Skin Sens. 1A, Muta. 2, Aquatic Chronic 2 |
|
methyl oct-2-ynoate |
111-12-6 |
Skin Sens. 1A (H317) |
|
dinotefuran |
165252-70-0 |
Acute Tox. 4, Aquatic Acute 1, Aquatic Chronic 1 |
Updated Substance Classifications
The following entries replace existing classifications in Annex VI and reflect updated hazard information for substances already listed under the CLP Regulation.
|
Substance |
CAS Number |
Hazard Classification |
|
2-phenylpropene; α-methylstyrene |
98-83-9 |
Flam. Liq. 3, Carc. 2, STOT SE 3, Eye Irrit. 2, Skin Sens. 1B, Aquatic Chronic 2 |
|
pethoxamid |
106700-29-2 |
Acute Tox. 4, Skin Sens. 1A, Aquatic Acute 1, Aquatic Chronic 1 |
|
tetraphosphorus trisulphide |
1314-85-8 |
Flam. Sol. 1, Self-heat. 1, Acute Tox. 4 |
|
1,1-dichloroethylene |
75-35-4 |
Flam. Liq. 1, Carc. 1B, Muta. 2, Acute Tox. 1/3, STOT RE 1 |
|
isophorone di-isocyanate |
4098-71-9 |
Acute Tox. 1, Skin Corr. 1, Resp. Sens. 1, Skin Sens. 1A |
|
folpet |
133-07-3 |
Carc. 2, Acute Tox. 2, STOT RE 1, Eye Dam. 1, Aquatic Acute 1 |
|
captan |
133-06-2 |
Carc. 2, Repr. 2, Acute Tox. 2, STOT RE 1, Aquatic Acute 1 |
|
clopyralid |
1702-17-6 |
Eye Dam. 1, Aquatic Chronic 1 |
|
proquinazid |
189278-12-4 |
Carc. 2, STOT RE 1, Aquatic Acute 1, Aquatic Chronic 1 |
|
3-iodo-2-propynyl butylcarbamate |
55406-53-6 |
Acute Tox. 2/4, STOT RE 1, Eye Dam. 1, Aquatic Acute 1 |
Next Steps
Stakeholders, particularly manufacturers, importers, and downstream users, should review the updated classifications and begin preparing to update safety data sheets, product labels, and internal documentation. The new rules can be applied early from 10 July 2025, but compliance will become mandatory from 1 February 2027.
The full text of Delegated Regulation (EU) 2025/1222 is available here.
We acknowledge that the above information has been compiled from European Commission.
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