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California’s OEHHA Adds New Toxicity Endpoint for Bisphenol S BPS in Proposition 65 List

2025-02-26 Reference source : Office of Environmental Health Hazard Assessment

Proposition 65 Toxicological Data Public Health Toxic to Reproduction Bisphenol S California Office of Environmental Health Hazard Assessment OEHHA New Toxicity Endpoint Male Reproductive Toxicity


The California Office of Environmental Health Hazard Assessment (OEHHA) has expanded the Proposition 65 listing for Bisphenol S (BPS) to include male reproductive toxicity, effective January 3, 2025.  

 

BPS Use and Health Concerns 

BPS (CAS No. 80-09-1) is commonly used in plastics, food packaging, and thermal paper receipts, often as a substitute for Bisphenol A (BPA). However, scientific findings suggest that BPS, like BPA, may disrupt hormone function and harm reproductive health. 

 

The Proposition 65 List 

Proposition 65 requires California to maintain a list of chemicals known to cause cancer, reproductive harm, or both. These chemicals may be present in pesticides, household products, food, drugs, dyes, and solvents, as well as in manufacturing and construction materials. Some are also by-products of chemical processes. 

 

New Toxicity Endpoint Added 

BPS was first added to the Proposition 65 list on December 29, 2023, due to its effects on female reproductive toxicity. Following a determination by the Developmental and Reproductive Toxicant Identification Committee (DARTIC), acting as the State’s Qualified Experts published on December 12, 2024, the OEHHA expanded the listing to include male reproductive toxicity. 

This update strengthens California’s efforts to protect public health by raising awareness of the potential risks of BPS exposure. From January 3, 2026, businesses are required to provide warnings if their products contain high levels of BPS that could harm male reproductive health. 

 



We acknowledge that the above information has been compiled from Office of Environmental Health Hazard Assessment.

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