HSE Opens Consultation on Draft Recommendation to Add Three Substances to UK REACH Authorisation List

On 4 November 2025, the UK Health and Safety Executive (HSE) launched a public consultation on its draft recommendation to include three substances in Annex 14 (the Authorisation List) of UK REACH. This is the first time that substances have been proposed for inclusion in the Authorisation List since the UK’s withdrawal from the European Union.

Three Substances Proposed for Inclusion

The three substances prosed for inclusion are:

• 2-ethylhexyl 10-ethyl-4,4-dioctyl-7-oxo-8-oxa-3,5-dithia-4-stannatetradecanoate (DOTE) (CAS No. 15571-58-1)
• *Reaction mass of DOTE and 2-ethylhexyl 10-ethyl-4-[[2-[(2-ethylhexyl)oxy]-2-oxoethyl]thio]-4-octyl-7-oxo-8-oxa-3,5-dithia-4-stannatetradecanoate (MOTE)
• Tetraethyl lead (TEL) (CAS No. 78-00-2)

All three substances are classified as toxic to reproduction under Article 57(c) of UK REACH and are already listed in Annex 14 of the EU REACH Regulation.

Consultation Open Until 4 February 2026

Stakeholders are invited to submit comments by 4 February 2026, providing information specific to Great Britain on current uses, exposure scenarios, possible exemptions, and the availability of safer alternatives. Following the consultation, the HSE will finalise its recommendation and submit it to the UK Secretary of State, and the Scottish and Welsh Ministers for a final decision.

Implications for Industry

Once adopted, authorisation will be required for the use or placing on the market of these substances in Great Britain after the applicable sunset dates, which are expected to be 18 to 24 months after inclusion in Annex 14.

Additional Substances for Future Prioritisation

In parallel, the HSE is inviting interested parties to submit GB-specific information on two further substances to support future prioritisation work:

• Reaction products of 1,3,4-thiadiazolidine-2,5-dithione, formaldehyde and 4-heptylphenol (branched and linear), with ≥ 0.1 % w/w 4-heptylphenol (branched and linear) (several CAS numbers including 1471311-26-8 and 93925-00-9)
• 4,4′-bis(dimethylamino)-4″-(methylamino)trityl alcohol, with ≥ 0.1 % of Michler’s ketone or Michler’s base (CAS No. 561-41-1)

This information will help the HSE prepare future recommendations for inclusion in the Authorisation List.

Access to Consultations and Supporting Documents

All related consultation documents, including the draft recommendation, technical rationale, and background information for both the proposed and future substances, are available on the HSE consultation portal here.