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Japan Updates New Chemical Substances List: 157 Substances Added

2025-03-28 Reference source : Ministry of Health, Labour and Welfare (MHLW) & Workplace Safety Portal-Japan

Chemical inventory Chemical notification/ registration ISHL MHLW New substances Japan Update


On 27 March 2025, the Japanese Ministry of Health, Labour and Welfare (MHLW) added 157 new chemicals to the New Chemicals List under the Industrial Safety and Health Act (ISHA). This update was announced through an ISHA Notice that was released on that same day.  

Details such as the name, ISHA official gazette serial number, chemical and structural formula of the new chemical substances are published alongside the updated list on the MHLW's Workplace Safety Portal. The list is available here

 

Previous addition: 131 New Chemical Substances in December 2024  

This update follows the addition of 131 chemical substances to the list announced in a notice issued under ISHA on December 27, 2024, and published through the MHLW' Workplace Safety Portal. The update can be found here

 
Obligations for Stakeholders  

At present, the list of chemicals known as the Existing and New Chemical Substances (ENCS) list includes 72,601 items. The Industrial Safety and Health Act mandates that manufacturers, importers, or companies in Japan notify the MHLW before producing or importing such chemicals. The notification must include the name of the new chemical compound and the specifics of its danger evaluation to protect industrial workers' health.  



We acknowledge that the above information has been compiled from Ministry of Health, Labour and Welfare (MHLW) & Workplace Safety Portal-Japan.

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